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Science Thread

  1. Char said:
    It's better to have an imperfect but still good society vs a totalitarian regime.

    it's better for humans to be free to choose whatever ends they desire!
    buggers who think they know better should just die!

    sure some rules (rules that are agreed upon by the whole) and etc will be required, but disgusting things like utilitatarianism should just explode!

    /anyway let's not derail this thread. keep it science guys.

    Posted 5 years ago # Quote
  2. odysseus said:

    I'm not discussing cloning (I also don't particularly feel that there's anything wrong with it, either). I'm discussing the combination of genes from two different people in an artificial manner. With current technology I know this is possible, but I'm not sure if sperm is required (I'm fairly certain it is... with current technology).

    It would not be practical but yes an embryo can be created from two eggs.
    It took 460 attempts.
    http://cmbi.bjmu.edu.cn/news/0404/82.htm
    In theory it should be possible to make eggs or sperm from stem cells.
    So it might be possible to even create an offspring from two males as well.
    http://med.stanford.edu/ism/2009/october/germ-cells.html

    Posted 5 years ago # Quote
  3. Char said:
    article quotes/paraphrases

    460 attempts the first time, 200 the next, 30 after that... and normally 1.378 attempts *pulling numbers from my ass, naturally.* After long enough science processes becomes engineering, and engineering processes become technical processes. Today's nMRI technicians were the scientists of yesterday.

    Anyways, I think we've exhausted this topic and beat it to death. Unless someone wants to roll over her head with a tractor, does anyone want to discuss something new?

    megumitractor.gif

    Posted 5 years ago # Quote
  4. pondering about it, wouldnt there be some masculine-in-thought like females as well? how would you address that?

    Posted 5 years ago # Quote
  5. cheese_cake said:
    pondering about it, wouldnt there be some masculine-in-thought like females as well? how would you address that?

    Doesn't bother me in the least, it's the hormones that are man's downfall. Well, now that that's out of the way, the philosophy is a derivative of what's known as postgenderism, and whether it's pursued or not, I think that seeing the involved science become mainstream could very well show significant improvements in standards of living.

    Hmmm... how do people feel about designer babies? How about so-called cybernetics?

    Posted 5 years ago # Quote
  6. tking abt designer babies, i think i'd be more advantageous for a government to mass produce them... in a way similar to brave new world.

    the only problem i have with it is if u want a certain baby but dont have the means to pay for it while having to go through the peer pressure of being around people who can. it also encourages the elite to be more elite....

    tho if i'm elite, i'd be all for it....

    Posted 5 years ago # Quote
  7. Worth a watch. I found it more interesting and entertaining, even though the man needs to learn to speak a little slower. My guess is that he gets nervous in front of crowds.

    Posted 5 years ago # Quote
  8. THIS is how you make cell biology awesome...put it to music and use 3D graphics :D

    Posted 5 years ago # Quote
  9. In other news, it seems that more citizens care about the issue of global warming than the importance of the ecconomics that affect their livelyhoods.

    They probably just polled the people that happen to live in cities that will be most affected when the tides start to intrude upon their homes and metropolitain areas.

    http://www.irishtimes.com/newspaper/world/2011/1008/1224305454767.html

    Anyone here just happen to live near the sea? Maybe it might be a good idea to consider moving inland a little bit, before its too late. Like those poor folks in Venice.

    The tide is rising, since Canada did lose two large hunks of ice in their northern territory.

    Posted 4 years ago # Quote
  10. Bumping this thread because I really don't know where the hell else to put this.

    http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1003587

    However, expressing an engineered HIV-1 long terminal repeat (LTR) site-specific recombinase (Tre), shown to excise integrated proviral DNA in vitro, may provide a novel and highly promising antiviral strategy. We report here the conditional expression of Tre-recombinase from an advanced lentiviral self-inactivation (SIN) vector in HIV-infected cells. We demonstrate faithful transgene expression, resulting in accurate provirus excision in the absence of cytopathic effects. Moreover, pronounced Tre-mediated antiviral effects are demonstrated in vivo, particularly in humanized Rag2−/−γc−/− mice engrafted with either Tre-transduced primary CD4+ T cells, or Tre-transduced CD34+ hematopoietic stem and progenitor cells (HSC). Taken together, our data support the use of Tre-recombinase in novel therapy strategies aiming to provide a cure for HIV.

    Since this treatment is clearly not immunogenic enough to lose effectiveness (at least in the time the trial was conducted), we will have a new HIV antiviral therapy! As if three kinds wasn't enough.

    I don't know why I didn't think of using a recombinase this way. So simple yet so brilliant.

    Posted 2 years ago # Quote
  11. How are we going to control Africa's population now?

    Posted 2 years ago # Quote
  12. kudichan said:
    How are we going to control Africa's population now?

    The treatment sounds expensive so it might not change things there.

    Posted 2 years ago # Quote
  13. kudichan said:
    How are we going to control Africa's population now?

    The Genophage (aka sickle cell disease).

    Posted 2 years ago # Quote
  14. LOL at the posts in here.

    Posted 2 years ago # Quote
  15. HEY GUYS, YOU MIGHT HAVE AGE REDUCTION DRUGS/THERAPIES IN YOUR LIFETIME I AM NOT KIDDING

    http://www.cell.com/retrieve/pii/S0092867413015213

    Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but its causes are debated. We show that, during aging, there is a specific loss of mitochondrial, but not nuclear, encoded OXPHOS subunits. We trace the cause to an alternate PGC-1α/β-independent pathway of nuclear-mitochondrial communication that is induced by a decline in nuclear NAD+ and the accumulation of HIF-1α under normoxic conditions, with parallels to Warburg reprogramming. Deleting SIRT1 accelerates this process, whereas raising NAD+ levels in old mice restores mitochondrial function to that of a young mouse in a SIRT1-dependent manner. Thus, a pseudohypoxic state that disrupts PGC-1α/β-independent nuclear-mitochondrial communication contributes to the decline in mitochondrial function with age, a process that is apparently reversible.

    Posted 2 years ago # Quote
  16. Well that's part of the equation you still need to deal with the worn telemers to reverse aging.

    Posted 2 years ago # Quote
  17. and saggy boobies

    Posted 2 years ago # Quote
  18. http://jama.jamanetwork.com/article.aspx?articleid=1791497#Results(Recommendations)

    Most of you are too young to care but tl;dr, new hypertension (high blood pressure) guidelines came out and they raised the goal line for some groups

    Posted 2 years ago # Quote
  19. Monkey controls a robot and virtual avatars.

    Posted 2 years ago # Quote
  20. BRILLIANT!

    I felt nothing btw

    Posted 2 years ago # Quote

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